Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Distribution: Tissue Binding01:21

Drug Distribution: Tissue Binding

Upon entering the systemic circulation, drugs can distribute into the interstitial and intracellular fluid of various tissue cells. This distribution is facilitated by the binding of drugs to different cellular components within tissues, which may lead to drug accumulation in specific areas. Drugs bound to tissue components serve as reservoirs that release free drugs back into the system, prolonging the drug's overall action. However, this accumulation can also result in local toxicity.
For...
Factors Affecting Drug Distribution: Miscellaneous Factors01:19

Factors Affecting Drug Distribution: Miscellaneous Factors

Drug distribution in the human body is a complex process influenced by various individual factors, including age, pregnancy, obesity, diet, body water composition, pH levels, and specific disease conditions.
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: MYC Expression in Concert With BCL2 and BCL6 Expression Predicts Outcome in Chinese Patients With Diffuse Large B-Cell Lymphoma, Not Otherwise Specified.

PloS one·2018
Same author

Molecular characterization of nine suppressors of cytokine signaling (SOCS) genes from yellow catfish Pelteobagrus fulvidraco and their changes in mRNA expression to dietary carbohydrate levels.

Fish & shellfish immunology·2018
Same author

Staining Traditional Colloidal Gold Test Strips with Pt Nanoshell Enables Quantitative Point-of-Care Testing with Simple and Portable Pressure Meter Readout.

ACS applied materials & interfaces·2018
Same author

Preoperative systemic immune-inflammation index predicts prognosis of patients with oral squamous cell carcinoma after curative resection.

Journal of translational medicine·2018
Same author

Microfluidic Preconcentration Chip with Self-Assembled Chemical Modified Surface for Trace Carbonyl Compounds Detection.

Sensors (Basel, Switzerland)·2018
Same author

Efficacy of Telephone Follow-Up in Children Tonsillectomy with Day Surgery.

Indian journal of pediatrics·2018

Related Experiment Video

Updated: Jun 26, 2026

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins
10:21

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins

Published on: June 20, 2019

FAHFAs: structures, distribution, analytical methods, and health implications.

Tingyi Ke1, Xianping Li2, Jie Cheng1

  • 1College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541006, China; Beijing Engineering Research Center of Dairy, Beijing Technical Innovation Center of Human Milk Research, Beijing Sanyuan Foods Co., Ltd., Beijing 100163, China.

Food Chemistry
|June 24, 2026
PubMed
Summary

Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly discovered lipids linked to metabolic diseases. This review details their structure, function, and dietary presence, aiding further research and functional food development.

Keywords:
Bioactive lipidFAHFAFood-derived FAHFAHuman healthPhysiological function

More Related Videos

Quantification of Humic and Fulvic Acids in Humate Ores, DOC, Humified Materials and Humic Substance-Containing Commercial Products
12:55

Quantification of Humic and Fulvic Acids in Humate Ores, DOC, Humified Materials and Humic Substance-Containing Commercial Products

Published on: March 18, 2022

Related Experiment Videos

Last Updated: Jun 26, 2026

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins
10:21

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins

Published on: June 20, 2019

Quantification of Humic and Fulvic Acids in Humate Ores, DOC, Humified Materials and Humic Substance-Containing Commercial Products
12:55

Quantification of Humic and Fulvic Acids in Humate Ores, DOC, Humified Materials and Humic Substance-Containing Commercial Products

Published on: March 18, 2022

Area of Science:

  • Biochemistry
  • Lipidomics
  • Metabolic Research

Background:

  • Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are endogenous lipids implicated in type 2 diabetes, obesity, and cancer.
  • FAHFAs possess diverse biological activities, including metabolic regulation, anti-inflammatory, antioxidant, and immunomodulatory effects.
  • Significant scientific interest has grown following FAHFA discovery, driven by advances in analytical techniques and understanding of their roles.

Purpose of the Study:

  • To comprehensively review current research on FAHFAs.
  • To cover FAHFA structural characteristics, endogenous synthesis, metabolism, detection, dietary occurrence, and physiological functions.
  • To establish a framework for future FAHFA research, mechanism elucidation, and functional food development.

Main Methods:

  • Literature review of scientific research on FAHFAs.
  • Analysis of advancements in analytical technologies for FAHFA identification.
  • Synthesis of data on FAHFA biological activities and physiological roles.

Main Results:

  • Numerous FAHFA family members and isomers have been identified in various food sources.
  • The biological activities and physiological roles of FAHFAs have been increasingly elucidated.
  • Current research provides a foundation for understanding FAHFAs in health and disease.

Conclusions:

  • FAHFAs represent a critical area of lipid research with implications for metabolic health.
  • Further investigation is needed to clarify FAHFA mechanisms of action.
  • FAHFAs hold potential for the development of targeted functional foods.