Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies VII: Vascular Imaging

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...

Acute Kidney Injury II: Pathophysiology

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparison of Emergency Physicians' and Hospitalists' Attitudes Toward Fecal Occult Blood Testing in Gastrointestinal Bleeding.

The western journal of emergency medicine·2025

Same author

Cross-species mapping of psychedelic gene expression reveals links to the 5HT2A receptor, cortical layers, and human accelerated regions.

Research square·2025

Same author

Variability in Venous Thromboembolism Prophylaxis in Patients With Orthopedic Trauma at a Level 2 Trauma Center.

Journal for healthcare quality : official publication of the National Association for Healthcare Quality·2025

Same author

Teaching residents to teach: A pilot study for an innovative online curriculum.

AEM education and training·2024

Same author

Creating an Asynchronous Curriculum for Your Emergency Medicine Residency.

MedEdPublish (2016)·2023

Same author

Does Inclusion of Emergency Medicine (EM) Residents in ECG Screening for STEMI Change the Time to Catheterization Lab Activation?

Critical pathways in cardiology·2023

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

Intravenous Contrast Causes Nephropathy.

Eric Steinberg¹, Joseph Bove¹

¹Department of Emergency Medicine, St. Joseph's University Medical Center, 703 Main Street, Paterson, NJ 07503, USA.

Emergency Medicine Clinics of North America

|June 24, 2026

Summary

This summary is machine-generated.

Intravenous contrast rarely causes acute kidney injury (AKI). Current evidence shows contrast is safe for most patients, and overly cautious policies hinder necessary diagnoses.

Keywords:

AKI CIN CKD Contrast Contrast-induced nephropathy GFR Kidney disease Kidney injury

More Related Videos

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

Direct Drug Delivery to Kidney via the Renal Artery

Direct Drug Delivery to Kidney via the Renal Artery

Published on: April 17, 2021

Related Experiment Videos

Last Updated: Jun 26, 2026

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

Direct Drug Delivery to Kidney via the Renal Artery

Direct Drug Delivery to Kidney via the Renal Artery

Published on: April 17, 2021

Area of Science:

Nephrology
Radiology
Medical Imaging

Background:

Historically, intravenous contrast agents were believed to frequently cause nephropathy.
Early studies lacked controlled cohorts, leading to unsubstantiated concerns about contrast-induced nephropathy.

Purpose of the Study:

To re-evaluate the causal link between intravenous contrast media and acute kidney injury (AKI).
To inform clinical practice regarding the safe use of contrast in patients with varying kidney function.

Main Methods:

Review of modern evidence and controlled cohort studies.
Analysis of guidelines and recommendations concerning contrast administration.

Main Results:

Recent research indicates contrast is seldom the direct cause of AKI.
Patients with estimated glomerular filtration rate ≥30 mL/min can receive contrast without prophylactic measures.
The term "contrast-associated AKI" is now preferred, highlighting correlation over causation.

Conclusions:

Intravenous contrast is a vital diagnostic tool, not inherently nephrotoxic.
Overly cautious protocols delay diagnosis and negatively impact patient care, particularly in emergencies.
Current evidence supports the safe use of contrast in a broader patient population.