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[Ultrastructure of the microcirculatory pathways of the lungs in chronic penumonia]
Abstract:
Study of the ultrastructure of the microcirculation tract in patients suffering from chronic pneumonia with bronchiectasis and abscess formation revealed involvement of all parts of the pulmonary and pleural microcirculation system, including intra-and extravascular disorders and changes in the vascular wall. Combination of rheological disorders and dyscoagulation in the microvessels with stable increase in vascular permeability and changes in the components of the aerohematic barrier leads to disturbances of metabolic and hemodynamic homeostasis in the lungs, advancement of the suppurative process, and increase of pulmonary hypertension.
Insights
Chronic pneumonia with bronchiectasis and abscesses damages the pulmonary microcirculation. This leads to metabolic and hemodynamic imbalances, worsening the condition and increasing pulmonary hypertension.
Area of Science:
- Pulmonary Medicine
- Vascular Biology
- Pathophysiology