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Artificial Intelligence in Caries Risk Assessment: Evaluating the Current Status of CAMBRA and Cariogram with Large
Caries Research
|June 25, 2026
Summary
Large language model (LLM)-based artificial intelligence (AI) can aid in early childhood caries risk assessment (CRA) when provided with specific guidelines. Performance varies by AI model and CRA tool, with numerical components posing challenges.
Area of Science:
- Artificial Intelligence in Healthcare
- Dental Public Health
- Pediatric Dentistry
Background:
- Caries risk assessment (CRA) is crucial for personalized early childhood caries management.
- Standardizing existing CRA tools in clinical practice is challenging.
- The efficacy of large language model (LLM)-based AI in applying CRA tools is not well understood.
Purpose of the Study:
- To evaluate ChatGPT and Google Gemini's ability to apply and interpret early childhood CRA tools.
- To assess AI performance under different prompting conditions (unguided, guideline-informed, guideline-only).
Main Methods:
- Thirty pediatric clinical vignettes (0-5 years) were analyzed using CAMBRA and Cariogram tools.
- ChatGPT and Google Gemini were prompted under three conditions.
- AI outputs were compared against expert classifications using categorical agreement, mean absolute error (MAE), quality, accuracy, and readability metrics.
Main Results:
- Guideline-informed and guideline-only prompting significantly improved AI performance (reduced MAE, enhanced quality and accuracy) compared to unguided prompting.
- ChatGPT demonstrated lower MAE than Gemini for the Cariogram tool.
- AI performance varied depending on the specific CRA tool and prompting strategy.
Conclusions:
- LLM-based AI systems show potential for supporting early childhood caries risk assessment, especially with guideline-based prompting.
- The effectiveness of AI in CRA is influenced by the specific AI model and the complexity of the CRA tool.
- Numerical or algorithmic aspects of tools like Cariogram present challenges for current LLM-based AI systems.
