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Related Experiment Video

Updated: Jun 27, 2026

Cellular Encapsulation in 3D Hydrogels for Tissue Engineering
09:37

Cellular Encapsulation in 3D Hydrogels for Tissue Engineering

Published on: October 26, 2009

Review 3D-Printed hydrogels for tissue engineering: a review.

Chao-Ming Su1, Jian-Jr Lee2,3, Ming-You Shie4,5

  • 1Advanced Therapeutic and Pharmaceutical Center, China Medical University Hospital, Taichung, Taiwan.

Frontiers in Bioengineering and Biotechnology
|June 26, 2026
PubMed
Summary

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This summary is machine-generated.

Three-dimensional (3D) bioprinting using hydrogels allows for the creation of advanced tissue engineering scaffolds. This review details recent hydrogel bioprinting techniques, materials, and applications for regenerative medicine.

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Three-dimensional (3D) bioprinting of hydrogels is a key strategy in tissue engineering.
  • It enables the creation of scaffolds with controlled architectures and biomimetic properties.
  • This review covers advances in the last two decades, with historical context.

Purpose of the Study:

  • To review recent advances in hydrogel-based 3D bioprinting.
  • To compare major hydrogel printing techniques.
  • To examine applications and translational challenges in tissue engineering.

Main Methods:

  • Discussion and comparison of light-based, extrusion-based, and inkjet-based hydrogel printing systems.
  • Examination of natural and synthetic hydrogels, including tough and composite hydrogels.
Keywords:
3D printingdigital light projection (DLP)natural hydrogelsprintable hydrogelsstereolithography (SLA)synthetic hydrogelstissue engineeringtough hydrogels

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Last Updated: Jun 27, 2026

Cellular Encapsulation in 3D Hydrogels for Tissue Engineering
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  • Review of strategies for improving mechanical durability and functional performance.

    • Main Results:

    • Hydrogel bioprinting techniques vary in resolution, fidelity, and cytocompatibility.
    • Natural and synthetic hydrogels offer complementary advantages in bioactivity, printability, and mechanics.
    • Advanced strategies enhance the performance of 3D-printed hydrogel constructs.

    Conclusions:

    • 3D bioprinting of hydrogels holds significant potential for diverse tissue engineering applications.
    • Key challenges include scalability, vascularization, standardization, and regulatory approval.
    • Further optimization is needed for successful clinical translation.