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Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

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Related Experiment Video

Updated: Jun 27, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

SEEG Implantation for Opercular Epilepsies.

Alexis Robin1, Philippe Kahane1, Dang Khoa Nguyen2,3

  • 1Neurology Department, CHU Grenoble Alpes, INSERM, U1216, Grenoble Institut Neurosciences, Grenoble, France.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|June 26, 2026
PubMed
Summary

Stereoelectroencephalography (SEEG) precisely maps rare insulo-opercular epilepsies, guiding surgical treatment. Tailored SEEG strategies improve diagnosis and outcomes for these complex focal epilepsy cases.

Keywords:
Implantation strategyOpercular EpilepsiesRadiofrequency thermocoagulationSeizure semiologyStereoelectroencephalography

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Operative Technique and Nuances for the Stereoelectroencephalographic (SEEG) Methodology Utilizing a Robotic Stereotactic Guidance System
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Operative Technique and Nuances for the Stereoelectroencephalographic (SEEG) Methodology Utilizing a Robotic Stereotactic Guidance System

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Related Experiment Videos

Last Updated: Jun 27, 2026

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
05:54

Stereo-Electro-Encephalo-Graphy (SEEG) With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

Published on: June 13, 2016

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring
11:28

Robotic-Guided Stereoelectroencephalography for Invasive Epilepsy Monitoring

Published on: June 13, 2025

Operative Technique and Nuances for the Stereoelectroencephalographic (SEEG) Methodology Utilizing a Robotic Stereotactic Guidance System
04:50

Operative Technique and Nuances for the Stereoelectroencephalographic (SEEG) Methodology Utilizing a Robotic Stereotactic Guidance System

Published on: June 9, 2023

Area of Science:

  • Neurosurgery
  • Epileptology
  • Neurology

Background:

  • Insulo-opercular epilepsies are rare and challenging focal epilepsy forms.
  • Often present with non-informative MRI and complex epileptogenic networks.
  • Pure opercular epilepsies are exceptionally rare in epilepsy surgery.

Purpose of the Study:

  • To highlight the critical role of stereoelectroencephalography (SEEG) in characterizing the epileptogenic zone (EZ) for insulo-opercular epilepsies.
  • To emphasize the necessity of individualized SEEG implantation strategies for complex epilepsy surgery.
  • To evaluate SEEG as a diagnostic and potentially therapeutic tool in these rare epilepsy types.

Main Methods:

  • Utilizing stereoelectroencephalography (SEEG) for precise localization of the epileptogenic zone (EZ).
  • Employing individualized SEEG electrode implantation strategies, combining orthogonal and oblique approaches.
  • Integrating anatomical, functional, and semiological data for hypothesis-driven SEEG planning.

Main Results:

  • SEEG enables accurate characterization of the EZ in rare insulo-opercular epilepsies.
  • Individualized SEEG implantation provides comprehensive coverage of complex epileptogenic networks.
  • SEEG can guide surgical treatment and, in select cases, serve as a therapeutic intervention (radiofrequency thermocoagulation).

Conclusions:

  • Hypothesis-driven, patient-specific SEEG is essential for evaluating and treating pure opercular and insulo-opercular epilepsies.
  • Tailored SEEG coverage enhances diagnostic accuracy and targeted therapeutic interventions.
  • Improved surgical outcomes and minimized risks are achievable with strategic SEEG approaches.