Related Experiment Video
Updated: Jun 30, 2026

06:52
The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project
Published on: November 12, 2009
Feasibility and Acceptability of a Virtual Single-Session Biofeedback Intervention Targeting Circulation, Heart Rate,
Lindsay G Flegge1,2, Jill C Penman2,3, Crystal Tracy4
1Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA.
Global Advances in Integrative Medicine and Health
|June 29, 2026
Summary
This pilot study shows virtual biofeedback is feasible and acceptable for rural chronic pain patients. The Mind Meter intervention significantly reduced anxiety and improved temperature.
Area of Science:
- Neuroscience
- Pain Management
- Digital Health
Background:
- Chronic pain impacts 20% of Americans, with rural populations facing access barriers to treatments like biofeedback.
- Geographic isolation and provider shortages limit evidence-based intervention delivery in rural areas.
Purpose of the Study:
- To evaluate the feasibility, acceptability, and preliminary effectiveness of the Mind Meter virtual biofeedback intervention for rural adults with chronic pain.
- To assess the potential of a neuroscience-based, group biofeedback program delivered remotely.
Main Methods:
- A pilot study involving 21 rural adults with chronic pain who completed a single-session virtual Mind Meter group.
- Intervention integrated pain neuroscience education and biofeedback using affordable equipment (pulse oximeters, skin thermometers).
- Feasibility (enrollment, adherence, completion), acceptability (questionnaire), and preliminary effectiveness (pre-post changes in heart rate, temperature, pain, anxiety) were measured.
Main Results:
- Adherence was 100%, exceeding the 80% goal; acceptability was high (90.5% rated ≥4/5).
- Significant pre-post improvements were observed in anxiety (P < 0.001) and temperature (P = 0.003).
- Pain reduction (P = 0.025) lost statistical significance after correction; heart rate showed no change (P = 0.615).
Conclusions:
- Virtual Mind Meter is a feasible and highly acceptable intervention for rural chronic pain patients.
- The program shows promise for reducing anxiety and improving physiological measures like temperature.
- Adjustments to recruitment strategies are needed due to lower-than-expected enrollment, but preliminary outcomes support further development.
