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Updated: Jul 1, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Dengue epidemic in Northern Peru (2024): analysis of 2,449 cases
Luis Ángel Rodríguez-Chávez1, Maribel Luz Esteban-Dionicio2
1Universidad Privada Antenor Orrego, Trujillo, Perú; Centro de Investigación en Medicina Interna, Hospital de Alta Complejidad La Libertad Virgen de la Puerta, EsSalud, Trujillo, Perú.
Objective:
To describe the clinical profile and comorbidities of confirmed dengue cases during the 2024 epidemic in northern Peru.
Methods:
A retrospective case series including 2,449 patients with confirmed dengue treated at a tertiary care hospital was conducted. Dengue was classified according to World Health Organization criteria, and demographic characteristics, clinical manifestations, and comorbidities were analyzed.
Results:
Of the cases, 54.4% corresponded to dengue without warning signs, 45.0% to dengue with warning signs, and 0.7% to severe dengue. The most frequent manifestations were fever, headache, retro-orbital pain, and lumbar pain. Patients with greater clinical severity more frequently presented chest pain, encephalopathy, and signs of hemodynamic compromise. Additionally, a higher frequency of cardiovascular and renal comorbidities was observed in these patients.
Conclusions:
The epidemic was characterized by a high proportion of cases with warning signs, and a higher frequency of comorbidities was observed in patients with greater clinical severity.
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