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Infective Endocarditis-Associated Glomerulonephritis Caused by Streptococcus cristatus: A Case Report
Yuta Nakagawa1, Chie Yamamoto1,2, Mari Morimoto3
1Department of Infection Control and Laboratory Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Infective endocarditis (IE) can mimic ANCA-associated vasculitis with purpura and kidney injury. Prompt diagnosis via blood cultures and echocardiography is crucial to avoid incorrect immunosuppression for this infection-related glomerulonephritis.
Area of Science:
- Nephrology
- Infectious Diseases
- Cardiology
Background:
- Infective endocarditis (IE) can lead to systemic embolic and immune-mediated complications like infection-related glomerulonephritis (IRGN).
- IE-associated glomerulonephritis (IEAGN) may present with symptoms mimicking primary small-vessel vasculitis, including purpura, nephritic urinary findings, and ANCA positivity.
- Misdiagnosis risks inappropriate immunosuppression if the underlying infection is not identified.
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