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Updated: Jul 2, 2026

08:23
CIRCLE-Seq for Interrogation of Off-Target Gene Editing
Published on: November 1, 2024
From Blog to lab: testing messages to shift public opinion on gene editing
Luke S Wimpy1, Brandon R McFadden1, Kathryn A Stofer2
1Department of Agricultural Economics and Agribusiness, University of Arkansas, Fayetteville, AR, United States.
Frontiers in Bioengineering and Biotechnology
|July 1, 2026
Summary
Communicating gene editing safety is key for biotechnology adoption. Presenting information within its specific application context (agriculture or medicine) is more effective for public understanding than messenger type or message framing.
Area of Science:
- Biotechnology Communication
- Public Opinion Research
- Gene Editing Technologies
Background:
- Public acceptance is crucial for advancing biotechnology in agriculture and medicine.
- Effective communication strategies are needed to shape public perception of gene editing safety.
Purpose of the Study:
- To identify communication strategies that most effectively influence public opinion on gene editing safety.
- To evaluate the impact of messenger, message framing, and application context on public perception and knowledge.
Main Methods:
- A randomized survey experiment with 3,200 U.S. respondents.
- Participants viewed one of eight videos varying in messenger, message framing, and application context.
- Analysis focused on opinion change and knowledge retention across different communication conditions.
Main Results:
- Video interventions generally improved perceptions of gene editing safety.
- Application context significantly impacted knowledge retention; context-aligned information led to better recall.
- Messenger type and message framing had minimal effects on knowledge outcomes.
Conclusions:
- The application context of gene editing information is more critical for public understanding than messenger or framing.
- Tailoring communication to specific fields (agriculture or medicine) enhances public comprehension and acceptance of gene editing.
- Findings provide actionable insights for science communicators, policymakers, and stakeholders.
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