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ChatGPT, Claude Sonnet, and Grok Display Similarly Low Rates of Accuracy in Identifying Image-Based Orthopaedic
Ahmad R Alhankawi1, Collin L Braithwaite2, Alejandro M Holle1
1Mayo Clinic Alix School of Medicine Scottsdale Arizona U.S.A.
Arthroscopy, Sports Medicine, and Rehabilitation
|July 1, 2026
Summary
Generative artificial intelligence (AI) models like ChatGPT 4.0, Grok 2, and Claude 3.5 Sonnet show poor accuracy in identifying common sports injuries from radiologic images. Current AI platforms are not recommended for image-based orthopaedic diagnosis.
Area of Science:
- Orthopaedic imaging analysis
- Artificial intelligence in medicine
- Diagnostic accuracy assessment
Background:
- The increasing popularity of AI necessitates understanding its diagnostic capabilities and limitations.
- Radiologic imaging is crucial for diagnosing sports-related pathologies.
Purpose of the Study:
- To evaluate the accuracy of AI in identifying common sports injuries from radiologic images.
- To compare the performance of ChatGPT 4.0, Grok 2, and Claude 3.5 Sonnet.
Main Methods:
- Five common sports pathologies (ACL tears, PCL tears, meniscal tears, chondral pathologies, rotator cuff tears) were selected.
- Fifty images per pathology were collected from imaging databases (radiography, CT, MRI), including normal images.
- Receiver operator characteristic curves and area under the curve (AUC) values were calculated to assess AI accuracy.
Main Results:
- ChatGPT 4.0, Grok 2, and Claude 3.5 Sonnet identified pathologies in 23.6%, 15.7%, and 17.1% of diseased images, respectively.
- AUC values were low (ChatGPT: 0.21, Grok: 0.16, Claude: 0.15), indicating poor performance.
- No significant differences in accuracy were observed between the AI platforms overall or for specific pathologies.
Conclusions:
- Current generative AI models demonstrate significant limitations in accurately diagnosing sports-related pathologies from radiologic images.
- The accuracy rates and AUC values suggest these AI tools are not yet suitable for clinical use in orthopaedic image-based diagnosis.
- Further development is required before AI can be reliably integrated into diagnostic workflows for musculoskeletal conditions.
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