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Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Neoplastic Diseases.
Beatrice J Tiangco1, Aldrich Ivan Lois D Burog2, Ann Meredith Garcia-Trinidad3
1Institute of Clinical Epidemiology, National Institutes of Health, University of the Philippines Manila, Manila, Philippines.
Acta Medica Philippina
|July 1, 2026
Summary
This study provides evidence-based cancer screening recommendations for the Philippines, including specific guidelines for early detection of liver, cervical, oral, and breast cancers. It aims to guide primary care in reducing cancer mortality.
Area of Science:
- Oncology
- Public Health
- Clinical Practice Guidelines
Background:
- Cancer is a leading cause of death in the Philippines, necessitating national early detection strategies.
- The country currently lacks a comprehensive national cancer screening program.
- This guideline addresses screening for 10 specific cancers.
Purpose of the Study:
- To develop evidence-based clinical practice guidelines (CPGs) for cancer screening in the Philippines.
- To provide recommendations for early detection of retinoblastoma, nasopharyngeal, liver, cervical, oral, colorectal, breast, prostate, lung, and gastric cancers.
- To guide primary care providers in implementing cancer screening protocols.
Main Methods:
- The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was utilized.
- A systematic literature search was conducted up to August 2021 to gather evidence on net benefit or harm.
- Recommendations were finalized through consensus among multiple stakeholder groups.
Main Results:
- Twenty recommendations were formulated for 10 cancer types.
- Strong recommendations support screening for hepatocellular carcinoma (ultrasound with AFP), cervical cancer (ages 30-65), oral cancer (ages 35+), and breast cancer (ages 50-69).
- Strong recommendations advise AGAINST screening for cervical cancer in women aged 21-29 and against HPV co-testing.
Conclusions:
- The Neoplastic Diseases Task Force developed 20 recommendations based on systematic evidence review.
- These guidelines offer crucial direction for cancer screening and risk assessment at the primary care level.
- The recommendations aim to improve early cancer detection and management in the Philippines.
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