Related Experiment Video
Updated: Jul 3, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
Published on: July 21, 2023
Reduction in Heart Failure Hospitalizations Through Real-World HeartLogicTM Alert Response - A Multicenter Study in
Takafumi Oka1, Mitsuyoshi Takahara2, Shohei Kataoka3
1Department of Cardiovascular Medicine, the University of Osaka Graduate School of Medicine.
Responding to HeartLogic alerts may reduce heart failure hospitalizations. This real-world study found that timely alert responses significantly attenuated the increase in heart failure hospitalizations over time.
Area of Science:
- Cardiology
- Medical Technology
- Health Services Research
Background:
- Heart failure (HF) is a progressive condition with increasing hospitalization rates.
- HeartLogic (HL) is a remote monitoring system for early detection of HF decompensation.
- Real-world data is needed to assess the impact of HL alert responses on HF hospitalizations.
Purpose of the Study:
- To evaluate if responses to HeartLogic alerts can reduce HF-related hospitalizations.
- To compare HF hospitalization rates before and after HL alert activation.
- To assess the impact of alert responsiveness on hospitalization trends.
Main Methods:
- Retrospective analysis of 246 patients with HL-enabled devices across 8 Japanese centers.
- Categorization of patients into alert-responsive (AR) and non-responsive (NR) groups.
- Comparison of HF hospitalization rates during alert-off and alert-on periods.
Main Results:
- HF hospitalizations increased from 77.1 to 182.6 per 1,000 person-years after alert activation.
- The increase in HF hospitalizations was significantly higher in the NR group (3.24-fold) compared to the AR group (1.28-fold).
- Alert responsiveness significantly attenuated the relative increase in HF hospitalizations (adjusted relative ratio 0.40; P=0.025).
Conclusions:
- Real-world alert responses to HeartLogic may reduce HF hospitalizations.
- Proactive management of HF decompensation through alert responses can potentially lower healthcare costs.
- This study highlights the clinical utility of remote monitoring systems in managing chronic diseases like heart failure.
Related Concept Videos
Heart Failure V: Medical Management
Heart Failure VI: Adjunct Therapies
Heart Failure III: Clinical Manifestations
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Heart Failure II: Pathophysiology
Rheumatic Heart Disease III: Medical Management
