Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Neuronal Communication

Neuronal Communication

Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...

Electrical Synapses

Electrical Synapses

Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
Gap junctions allow the current to pass directly from one cell to the next. In contrast, in the chemical synapse, the neurotransmitters carry the information through the synaptic cleft from one neuron to the next. They consist of two...

Neurochemical Transmission: Sites of Drug Action

Neurochemical Transmission: Sites of Drug Action

Neurochemical transmission, the conduction of electrical impulses between neurons mediated by neurotransmitters, plays a vital role in various physiological processes. Autonomic drugs exert their effects by modulating neurotransmission within the autonomic nervous system. For instance, drugs such as hemicholinium block the precursor uptake necessary for synthesizing acetylcholine, an essential autonomic neurotransmitter. Following synthesis, neurotransmitters are stored in vesicles. Metyrosine...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Polymeric Nanocarriers in Drug Delivery.

Pharmaceutical nanotechnology·2026

Same author

A case report of red degeneration of a uterine fibroid mimicking ovarian malignancy in the postpartum period: a diagnostic challenge.

Annals of medicine and surgery (2012)·2026

Same author

Uncovering functional divergence and cellular clusters with specific gene signatures in HNSCC clonal spheroids.

Cell communication and signaling : CCS·2025

Same author

From Structure to Functional Implications: Investigation of the Melon-Like Framework of Graphitic Carbon Nitride for Li-S Batteries.

ACS omega·2025

Same author

Acid vapor-induced enhanced electrical current rectification in phenothiazine-based electronic devices.

Chemical science·2025

Same author

Socio-Demographic Profile of Low Back Pain in Health Care Workers of a Tertiary Care Center of Eastern India - A Cross-Sectional Study.

Indian journal of occupational and environmental medicine·2025

Search research articles

Related Experiment Video

Updated: Jul 7, 2026

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Published on: July 18, 2025

Neuronal Interfaces in Bioelectronic Medicines for Unlocking Therapeutic Potential for ANS Issues.

Gunjan¹, Shaweta Sharma¹, Jyoti Pandey¹

¹Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, U.P., India.

Current Drug Research Reviews

|July 6, 2026

Summary

Bioelectronic devices precisely modulate the autonomic nervous system (ANS) for targeted disease treatment. Advancements in neurotechnology offer new therapeutic options for various conditions, though challenges remain in standardization and patient-specific applications.

Keywords:

Bioelectronic medicine autonomic nervous system cardiovascular disorders closed-loop systems inflammatory diseases neuromodulation

More Related Videos

Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation

Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation

Published on: December 22, 2020

Related Experiment Videos

Last Updated: Jul 7, 2026

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Published on: July 18, 2025

Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation

Focused Ultrasound Induced Blood-Brain Barrier Opening for Targeting Brain Structures and Evaluating Chemogenetic Neuromodulation

Published on: December 22, 2020

Area of Science:

Bioelectronic Medicine
Neurotechnology
Biocompatible Materials

Background:

Developments in neurotechnology, micro/nano-engineering, and biocompatible materials enable bioelectronic devices to modulate autonomic nervous system (ANS) activity.
These devices offer potential treatments for a variety of disorders by altering ANS function.

Purpose of the Study:

To explore how bioelectronic devices can modify ANS activity for treating various illnesses.
To discuss preclinical and clinical applications, electrode technology advancements, and challenges in neuromodulation.

Main Methods:

Review of preclinical and clinical studies on bioelectronic devices for ANS modulation.
Emphasis on electrode technology developments and their efficacy in treating metabolic, inflammatory, cardiovascular, and pelvic conditions.

Main Results:

Neuronal interfaces allow precise ANS neuromodulation for targeted therapies.
Clinical successes include vagus nerve stimulation (VNS) for rheumatoid arthritis and diabetes.
Challenges include foreign body response, glial scarring, and limited large-scale ANS-specific trials.

Conclusions:

Bioelectronic medicine offers targeted ANS therapies for conditions like inflammation, hypertension, and GI dysmotility.
Future research should focus on integrative approaches and technological advancements to overcome current limitations.
Case studies highlight the use of bioelectronic medicines in autonomic disorders.