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Dianionic Tetraalkynylmagnesate Complexes: A Strategy for Propargyl Amine Synthesis.

Yuto Arai1, Ryo Kobayashi1, Akira Matsumoto1

  • 1Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.

Organic Letters
|July 6, 2026
PubMed
Summary

This study introduces an efficient alkynylation reaction for N-aryl imines using tetraalkynyl magnesium ate complexes. The method yields propargylamines, which are valuable precursors for N-heterocycles.

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