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Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
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Related Experiment Video

Updated: Jul 10, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

The CHECK-IT Program - Controlling Hypertension in Black Communities through In-Person and Virtual Interventions.

Erika Cheng1, Brittany Smart2, Tatyana Roberts3

  • 1Associate Professor, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.

NEJM Catalyst Innovations in Care Delivery
|July 8, 2026
PubMed
Summary
This summary is machine-generated.

The CHECK-IT program improved hypertension control in Black adults by integrating home monitoring, education, and community health worker support. Over 60% of participants achieved blood pressure control, reducing disparities in cardiovascular disease care.

Related Experiment Videos

Last Updated: Jul 10, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
07:51

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

Area of Science:

  • Public Health
  • Cardiovascular Medicine
  • Health Equity

Background:

  • Black adults face disproportionately high hypertension rates and cardiovascular disease mortality in the U.S.
  • Systemic barriers like food and housing insecurity contribute to care access disparities.
  • Structural inequities necessitate innovative community-centered health interventions.

Purpose of the Study:

  • To evaluate the effectiveness of the Convenient Home Evaluation for Cardiovascular Health and Individual Tracking (CHECK-IT) program.
  • To address hypertension disparities among residents in high-risk Indianapolis neighborhoods.
  • To integrate home blood pressure monitoring, patient education, and community health worker support.

Main Methods:

  • The 4-month CHECK-IT program utilized a model adapted from the American Heart Association's "Check. Change. Control."
  • Participants received free blood pressure cuffs, training, educational curriculum, and automated text reminders.
  • Community health workers provided social support, assessed social determinants of health, and connected participants to resources, with virtual pharmacist support for medication management.

Main Results:

  • Over 60% of participants who completed the program achieved blood pressure control (<140/90 mmHg).
  • Average blood pressure reductions were 7 mmHg systolic and 4 mmHg diastolic.
  • The program demonstrated potential in addressing both medical and social drivers of hypertension disparities.

Conclusions:

  • The CHECK-IT program shows promise as a scalable, community-centered model for improving hypertension control.
  • Integrating home monitoring and social support effectively addresses barriers to care.
  • Further data collection is planned to assess long-term maintenance and referral outcomes.