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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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The CYB5R3 T117S missense variant is associated with attenuated riociguat efficacy in sickle cell disease

Katherine C Wood1,2, Seyed Mehdi Nouraie3, Mark T Gladwin4

  • 1Department of Medicine, Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Blood
|July 8, 2026
PubMed

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