Related Experiment Video
Updated: Jul 12, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
A rapidly involuting congenital haemangioma of the lower limb
Filipa Miranda Santos1, Joana Maria Gomes Moscoso2, Cristina Amaro3
1Pediatria, Hospital de São Francisco Xavier, Lisboa, Portugal filipadms11@gmail.com.
Abstract:
We report the case of a full-term male neonate born with a 5 cm vascular mass on the inner surface of the right thigh, diagnosed as a congenital haemangioma. Blood tests, including platelet count and coagulation parameters, were normal. Doppler ultrasound supported the diagnosis. Follow-up examinations at 1 week, 1 month and 2 months revealed progressive involution of the lesion, characterised by a growing peripheral pale halo, without ulceration or complications. Conservative management was adopted, and no interventions were required. This case highlights the natural regression of rapidly involuting congenital haemangiomas and underscores the importance of clinical observation, parental reassurance and multidisciplinary care in managing such cases.
Related Concept Videos
Veins of Lower Limbs
Formed by the union of the medial and lateral plantar veins, the posterior tibial vein, rising through the calf muscle, assimilates the fibular vein. The anterior tibial vein, a superior extension of the foot's dorsalis pedis vein, merges with the posterior tibial vein at the knee,...
Arteries of Lower Limbs
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Veins of Upper Limbs
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
Regulation of Angiogenesis and Blood Supply
Development of Blood Vessels
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
