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Updated: Jul 12, 2026

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
Published on: August 29, 2025
Delayed Diagnosis of Cystic Fibrosis and Nontuberculous Mycobacterial Infection in Refractory CRSwNP
Robert Greig1, Philipp Suter1, Rory Chan1
1Scottish Centre for Respiratory Research University of Dundee Dundee UK.
Abstract:
Cystic fibrosis is a systemic disease inherited in an autosomal recessive pattern associated with multisystem pathology including increased mucus viscosity and consequently reduced clearance. Here we report a case of a 31 year old woman who experienced several years of treatment-resistant type 2 low chronic rhinosinusitis. Repeat chest imaging revealed tree-in-bud change leading to a diagnosis of Mycobacterium abscessus and ultimately cystic fibrosis. She experienced a significant improvement following condensing M. abscessus eradication therapy and Kaftrio. This case outlines the importance of both considering atypical infection in treatment-resistant chronic rhinosinusitis and the underlying pathology such as cystic fibrosis.
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