Related Experiment Video
Updated: Jul 12, 2026
08:05
Bone Marrow Transplantation Platform to Investigate the Role of Dendritic Cells in Graft-versus-Host Disease
Published on: March 17, 2020
From Donation to Innovation: New Blood-Derived Products
Kerstin Wendland1,2, Kathleen Selleng1, Konstanze Aurich1
1Institute of Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany.
Summary
Transfusion medicine is evolving, creating advanced blood-derived therapeutics from plasma, red blood cells (RBCs), platelets, and stem cells for new medical treatments.
Area of Science:
- Transfusion Medicine
- Biotechnology
- Regenerative Medicine
Background:
- Emerging innovations are transforming donated blood into advanced therapeutic products.
- This review covers innovations in plasma, red blood cells (RBCs), platelets, donor stem cells, and cord blood.
Purpose of the Study:
- To summarize recent advancements in transfusion medicine.
- To highlight the development of novel blood-derived therapeutics.
Main Methods:
- Narrative review of current literature and emerging technologies.
- Analysis of innovations across various blood components.
Main Results:
- Plasma innovations include dried plasma and universal plasma for enhanced safety and stability.
- RBC advancements focus on preservation, artificial carriers, and universal blood cells.
- Platelet products are expanding into regenerative medicine.
- Stem cell and cord blood technologies offer scalable, donor-independent cell production.
Conclusions:
- Blood-derived therapeutics are becoming more engineered, customizable, and sustainable.
- These innovations address unmet clinical needs beyond traditional transfusion components.
More Related Videos
Related Concept Videos
01:22Bone Marrow Sampling and Transplants
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
01:15Blood Transfusion
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
02:45Blood Transfusion and Agglutination
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
01:24Tissue Transplantation
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
01:21Stem Cell Therapy for Tissue Regeneration
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...