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Related Concept Videos

Neural Regulation01:37

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

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Related Experiment Video

Updated: Jul 12, 2026

Intranuclear Microinjection of DNA into Dissociated Adult Mammalian Neurons
13:39

Intranuclear Microinjection of DNA into Dissociated Adult Mammalian Neurons

Published on: December 10, 2009

Neuronal Intranuclear Inclusion Disease: A Case Report With Insights Into Clinical Features and Potential Therapeutic

Lingqiong Xia1, Jianhua Chen1, Fuying Liu1

  • 1Department of Neurology, Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, Guizhou, China.

Case Reports in Neurological Medicine
|July 10, 2026
PubMed
Summary

Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disorder. Early diagnosis via skin biopsy and genetic testing is crucial for managing this progressive condition.

Keywords:
NIIDcase reportearly diagnosisneurological symptomsneuronal intranuclear inclusion disease

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Last Updated: Jul 12, 2026

Intranuclear Microinjection of DNA into Dissociated Adult Mammalian Neurons
13:39

Intranuclear Microinjection of DNA into Dissociated Adult Mammalian Neurons

Published on: December 10, 2009

Area of Science:

  • Neurology
  • Genetics

Background:

  • Neuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disorder.
  • It is characterized by intranuclear inclusion bodies in neurons and visceral organs.
  • NIID presents with diverse neurological symptoms, leading to frequent misdiagnosis.

Purpose of the Study:

  • To report a case of NIID diagnosed through skin biopsy and genetic testing.
  • To review the literature on NIID characteristics and diagnosis.
  • To emphasize the importance of early diagnosis and comprehensive treatment for NIID.

Main Methods:

  • Case report of NIID.
  • Diagnosis confirmed by skin biopsy.
  • Genetic testing utilized for confirmation.

Main Results:

  • Successful diagnosis of NIID in the reported case.
  • Demonstrated the utility of skin biopsy and genetic testing for NIID diagnosis.
  • Highlighted the varied clinical manifestations of NIID.

Conclusions:

  • Skin biopsy and genetic testing are valuable tools for diagnosing NIID.
  • Early identification and management are essential for improving patient outcomes in NIID.
  • Further research into NIID pathogenesis and treatment is warranted.