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Development of an Uncomplicated Mild Traumatic Brain Injury Model Modified by Weight-Drop Method and Evidenced by Magnetic Resonance Imaging
Published on: April 11, 2025
The Modified Brain Injury Guidelines Identify Low-Risk Traumatic Brain Injury Regardless of Age
Minta Bibb1, Tanner Smida2, Jeffrey Beyon2
1Department of Surgery, West Virginia University School of Medicine, Morgantown, WV, USA.
The American Surgeon
|July 25, 2026
Summary
The modified Brain Injury Guidelines (mBIG) effectively identify low-risk traumatic brain injury (TBI) patients. Advanced age and aspirin use did not increase the risk of radiographic progression or neurosurgical intervention in this study.
Area of Science:
- Neurosurgery
- Trauma Surgery
- Emergency Medicine
Background:
- The modified Brain Injury Guidelines (mBIG) classify traumatic brain injuries (TBI) to guide clinical decisions.
- Age is a known TBI risk factor but is not in the mBIG system.
- Aspirin's role in TBI outcomes requires further investigation.
Purpose of the Study:
- To assess radiographic progression and neurosurgical intervention rates in geriatric vs. non-geriatric patients stratified by mBIG.
- To determine if advanced age (>65) or aspirin use impacts TBI outcomes within the mBIG classification.
Main Methods:
- Retrospective observational study of blunt TBI patients (04/01/2018 - 03/01/2024).
- Primary outcome: neurosurgical intervention. Secondary outcome: radiographic intracranial hemorrhage progression.
- Univariable logistic regression analyzed age >65 and aspirin use.
Main Results:
- 1710 patients included: 13.5% mBIG 1, 8.1% mBIG 2, 78.4% mBIG 3.
- mBIG 1: 1.1% radiographic progression, 0% neurosurgical intervention.
- mBIG 2: 6.3% radiographic progression, 0.7% neurosurgical intervention.
- Neither age >65 nor aspirin use were associated with adverse outcomes.
Conclusions:
- The mBIG classification can identify low-risk TBI patients irrespective of age.
- Advanced age and aspirin use did not correlate with increased radiographic progression or need for neurosurgical intervention in this cohort.
- mBIG stratification remains a reliable tool for managing TBI patients.

