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FAMILIAL CARDIOMYOPATHY IN NIGERIA: A CASE REPORT
O S Ogah1,2, O S Folayan3,4, A Aje2
1Department of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Annals of Ibadan Postgraduate Medicine
|July 25, 2026
Summary
Familial dilated cardiomyopathy (DCM) presents unique challenges, especially in Nigeria. This case highlights hereditary patterns and the need for genetic screening and accessible treatments for familial DCM.
Area of Science:
- Cardiology
- Genetics
- Public Health
Background:
- Familial DCM (FDCM) is diagnosed with multiple first-degree relatives affected by idiopathic DCM or early unexplained death.
- Local data on FDCM in Nigeria is scarce, necessitating case reports to understand its prevalence and characteristics.
Purpose of the Study:
- To report the clinical manifestations of FDCM in a Nigerian family.
- To emphasize the role of genetics in FDCM pathogenesis.
- To address the lack of local data on familial dilated cardiomyopathy.
Main Methods:
- Case report of a 22-year-old male diagnosed with DCM.
- Detailed clinical examination, echocardiography, and family history assessment.
- Review of treatment challenges and outcomes in a resource-limited setting.
Main Results:
- The index patient presented with advanced heart failure symptoms.
- Echocardiography confirmed DCM; family history revealed an autosomal dominant inheritance pattern.
- A younger sibling exhibited similar echocardiographic features, confirming hereditary transmission.
Conclusions:
- Genetic factors are critical in FDCM pathogenesis.
- Management is challenging in resource-limited settings, requiring early screening and adherence to treatment.
- Accessible genetic testing is vital for early diagnosis and intervention in at-risk populations.
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