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Management of Radiodermatitis in Patients With Head and Neck Cancer Undergoing Radiotherapy: A Scoping Review
Tâmara Taynah Medeiros da Silva1,2, Louise Constancia de Melo Alves Silva1,2, Thatiane Evelyn de Lima Fernandes1,2
1Department of Nursing Federal University of Rio Grande do Norte Natal Brazil.
Health Care Science
|July 25, 2026
Summary
This review explores head and neck cancer radiodermatitis management. Current research on topical agents and therapies is insufficient to recommend specific treatments for radiation dermatitis.
Area of Science:
- Oncology
- Dermatology
- Radiotherapy
Background:
- Head and neck cancer is globally prevalent, necessitating evidence-based treatment strategies.
- Radiodermatitis is a common side effect of radiotherapy for head and neck cancer.
- Innovative treatment strategies for radiodermatitis are under investigation.
Purpose of the Study:
- To conduct a scoping review of strategies for managing radiodermatitis in head and neck cancer patients undergoing radiotherapy.
- To identify and synthesize existing research on radiodermatitis prevention and treatment.
Main Methods:
- Adherence to Joanna Briggs Institute (JBI) scoping review methodology and PRISMA-ScR checklist.
- Comprehensive search of eight major scientific databases (March 2024).
- Selection of 21 articles published between 2011 and 2024, with a focus on clinical trials.
Main Results:
- China was the leading country in publications.
- Radiation Therapy Oncology Group (RTOG) criteria were commonly used for assessment.
- Evaluated interventions included pharmacological therapies, phototherapy/photobiomodulation, and dressings.
Conclusions:
- Numerous topical agents have been tested for radiodermatitis prevention and treatment.
- Current research quantity and quality are insufficient to support widespread approval of specific products.
- Further high-quality research is needed to establish definitive management guidelines.
