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Identification of the Novel HLA-C*16:248 Allele Using Next-Generation Sequencing

Makbule Nihan Somuncu1

  • 1Department of Medical Genetics, Faculty of Medicine, Necmettin Erbakan University, Konya, Türkiye.

HLA
|July 25, 2026
PubMed
Abstract

Keywords:
HLA‐C*16:248new HLA allelenext‐generation sequencing

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Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.