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Updated: Aug 5, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Left Atrial Appendage Exclusion via Right Minithoracotomy Using an Epicardial Clip Device During Minimally Invasive
Razan Salem1,2,3, Pawel Nawrocki1,2, Andreas Däuwel2,4
1Department of Cardiovascular Surgery, Heart Center Niederrhein, Helios Klinikum Krefeld, 47805 Krefeld, Germany.
This study shows a new epicardial clip technique for left atrial appendage (LAA) closure during minimally invasive mitral valve surgery is safe and effective. This method successfully prevents stroke in patients with atrial fibrillation (AF).
Area of Science:
- Cardiovascular Surgery
- Minimally Invasive Cardiac Procedures
- Electrophysiology
Background:
- Left atrial appendage (LAA) closure is recommended for atrial fibrillation (AF) patients to prevent stroke.
- Current minimally invasive techniques for LAA exclusion during mitral valve surgery are challenging.
- A novel epicardial clip device applied via right minithoracotomy is presented.
Purpose of the Study:
- To evaluate the feasibility and safety of a novel epicardial clip for LAA exclusion during minimally invasive mitral valve surgery.
- To assess the efficacy of this technique in preventing cardioembolic stroke in AF patients.
- To report the largest series of this specific LAA exclusion method.
Main Methods:
- 40 patients with AF undergoing minimally invasive mitral valve surgery via right minithoracotomy had concomitant LAA exclusion.
- An epicardial clip device was applied to the LAA base under direct vision after the intracardiac procedure.
- Successful closure was confirmed by intraoperative transesophageal echocardiography.
Main Results:
- 100% successful LAA clip deployment was achieved in all 40 patients.
- Mean operative, cardiopulmonary bypass, and cross-clamp times were recorded.
- In-hospital mortality was 0%; one patient had a stroke, and one required re-thoracotomy for bleeding.
Conclusions:
- Minimally invasive LAA exclusion using an epicardial clip via right minithoracotomy is feasible and safe.
- This technique achieves high deployment success rates without additional incisions.
- It offers a valuable stroke prevention strategy for AF patients undergoing minimally invasive valvular surgery.
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