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Updated: Aug 5, 2026
09:39
Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
Published on: February 7, 2021
Intelligent Hydrocolloid-Based Delivery Systems: Innovations in Pharmacy and Cosmetics
Karen Khachatryan1, Oskar Michalski2, Klaudia Michalska3
1Laboratory of Nanotechnology and Nanomaterials, Faculty of Food Technology, University of Agriculture in Krakow, Al. Mickiewicza 21, 31-120 Krakow, Poland.
Molecules (Basel, Switzerland)
|July 28, 2026
Summary
Hydrocolloid matrices are versatile platforms for drug and cosmetic delivery. This review details their advanced applications, mechanisms, and limitations in pharmaceutical and cosmetic formulations.
Area of Science:
- Materials Science
- Polymer Chemistry
- Pharmaceutics
Background:
- Hydrocolloids have evolved from rheology modifiers to functional delivery platforms.
- Hybrid matrices incorporate synthetic components for responsive functions.
Purpose of the Study:
- To review hydrocolloid-based systems for pharmaceutical and cosmetic delivery.
- To analyze how hydrocolloid properties influence matrix performance.
- To compare various trigger mechanisms within hydrocolloid matrices.
Main Methods:
- Literature review of hydrocolloid chemistry, network architecture, and responsive mechanisms.
- Analysis of pharmaceutical and cosmetic applications.
- Discussion of material properties, trigger systems, and delivery routes.
Main Results:
- Hydrocolloid properties (hydration, ionisation, etc.) dictate swelling, mechanics, and release.
- Diverse trigger mechanisms (pH, enzyme, thermal, etc.) are explored in hydrocolloid matrices.
- Applications span oral, transdermal, wound healing, regenerative medicine, and skincare.
Conclusions:
- Hydrocolloids offer advantages for controlled release and active stabilization.
- Limitations include burst release, mechanical strength, drug loading, and regulatory challenges.
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