Peri- and Intraarticular Injections with Isolable Treatment Effects in Recurrent Mandibular Dislocation: A Mapping...

Area of Science:

• Orthopedics
• Oral and Maxillofacial Surgery
• Regenerative Medicine

Background:

• Recurrent temporomandibular joint (TMJ) dislocation causes pain and functional impairment.
• Injectable therapies offer a minimally invasive approach to enhance TMJ stability.
• Existing evidence is often confounded by adjunctive treatments.

Purpose of the Study:

• To map and characterize injectable treatments for recurrent TMJ dislocation.
• To assess injectable therapies independently of non-injectable interventions.
• To evaluate the quality and scope of current evidence.

Main Methods:

• Comprehensive literature search of PubMed, Europe PMC, and BASE.
• Screening of reference lists and relevant reviews.
• Inclusion of studies where injectable treatment effects could be isolated.

Main Results:

• Five primary studies evaluated autologous blood, prolotherapy, and sclerosing agents.
• Most studies reported improved joint stability and reduced dislocations.
• Improvements in mouth opening, pain, and clicking were also noted.
• Evidence is limited by small sample sizes and heterogeneous methodologies.

Conclusions:

• The literature on injectable TMJ dislocation therapies is sparse and varied.
• While generally favorable outcomes are reported, robust conclusions cannot be drawn.
• Comparative effectiveness of specific injectable modalities remains undetermined.