[Multidimensional characterization of biofilm formation promoted by Mycobacterium tuberculosis Rv1904]

Zhongting Ji1, Lihan Yin2, Yuqing Xie1

  • 1Jiangsu Key Laboratory of Zoonosis, Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Jiangsu Interdisciplinary Center for Zoonoses and Biosafety, Yangzhou University, Yangzhou 225009, Jiangsu, China.

Summary

Rv1904 promotes biofilm formation in Mycobacterium tuberculosis (M. tb), enhancing drug resistance and survival. Thioacetazone (TB1) effectively inhibits this Rv1904-mediated biofilm development, offering a potential anti-tuberculosis drug target.