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Updated: Aug 7, 2026

Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Patient Preference for Contrast-Enhanced Mammography Compared to Breast MRI
Romuald Ferre1, Thad Benefield2, Cherie M Kuzmiak1
1Faculty, Division of Breast Imaging, Department of Radiology, CB #7510, UNC School of Medicine, Physicians' Office Building, Rm #118, Chapel Hill, NC, USA (R.F., C.M.K.).
Patients generally prefer contrast-enhanced mammography (CEM) over breast magnetic resonance imaging (MRI) due to reduced claustrophobia and shorter exam times. This preference is noted when diagnostic performance is considered comparable between the two imaging modalities.
Area of Science:
- Radiology and Imaging
- Patient-Reported Outcomes
- Medical Technology Assessment
Background:
- Contrast-enhanced mammography (CEM) is emerging as an alternative to breast MRI for specific clinical scenarios.
- While CEM's diagnostic performance is studied, patient preference data is less understood.
- Understanding patient preference is crucial for informed clinical decision-making.
Purpose of the Study:
- To systematically review and meta-analyze patient preference between CEM and breast MRI.
- To quantify the proportion of patients preferring CEM versus MRI.
- To identify factors influencing patient preference.
Main Methods:
- Systematic search of MEDLINE and Embase databases.
- Inclusion of prospective and survey-based studies reporting preference data.
- Random-effects meta-analysis of pooled preference proportions.
Main Results:
- Five studies with 395 participants were analyzed.
- A pooled 71.8% of participants preferred CEM over MRI (67.2%-75.9%).
- Excluding neutral responses showed 81.5% preference for CEM among those with a definite choice.
Conclusions:
- Patients more frequently prefer CEM to breast MRI, likely due to less claustrophobia and shorter examination times.
- Patient experience should be integrated into shared decision-making when both CEM and MRI are clinically viable.
- Findings do not imply diagnostic equivalence between CEM and MRI.
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