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Combined Effects of PFAS and Metals on Cognitive Function

Adeola Shogbaike1,2, Emmanuel Obeng-Gyasi1,2

  • 1Department of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, USA.

Environments (Basel, Switzerland)
|August 6, 2026
PubMed
Summary

Joint exposure to heavy metals and per- and polyfluoroalkyl substances (PFAS) impacts cognitive function, particularly memory, in older adults. Mixture analysis reveals PFAS as a key factor influencing cognitive decline with combined environmental contaminant exposure.

Keywords:
Bayesian kernel machine regressionCERADPFAScognitive functionenvironmental mixturesheavy metalsneurotoxicity

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