Related Experiment Video
Updated: Aug 8, 2026

The Participant-Reported Implementation Update and Score (PRIUS): A Novel Method for Capturing Implementation-Related Data Over Time
Published on: February 19, 2021
Governance-First Deployment of the Aims Innovations Research Management System to Accelerate Participant-Based Public
Allison E Curry1, Ryan P Warren1, Dominique G Ruggieri1
1All authors are with Aims Innovations, Inc., Lewes, DE. Johnathon P. Ehsani is also with the Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Abstract:
Participant-based studies face fragmented workflows. We describe implementation of the Aims Innovations Research Management System, a cloud-based unified platform that supports the operations pipeline and includes participant-facing AI agents for outreach, screening, consent, and follow-up. Controls include private AI endpoints with no-training assurances, study isolation, human handoff thresholds, HIPAA (Health Insurance Portability and Accountability Act) safeguards, and tamper-evident audit logging. As of June 2026, 10 academic institutions completed governance reviews and initiated studies across diverse research designs. An initial pilot suggests there are efficiency gains, which warrants multisite evaluation. (Am J Public Health. 2026;116(10):1514-1519. https://doi.org/10.2105/AJPH.2026.308603).
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