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Racial, Socioeconomic, and Comorbidity-Associated Disparities in Acute Pancreatitis
Qilin Cao1, Shady Barsoom2, Aziz M Merchant3
1Department of Pathology, New York University Grossman School of Medicine, New York, New York.
The Journal of Surgical Research
|August 14, 2026
Summary
Racial and socioeconomic factors significantly impact acute pancreatitis (AP) causes and outcomes. Identifying at-risk groups is crucial for targeted interventions to reduce disparities in AP.
Area of Science:
- Gastroenterology
- Health Services Research
- Health Disparities
Background:
- Acute pancreatitis (AP) presents a substantial medical and financial burden in the US.
- Despite treatment advancements, significant disparities in AP etiology and outcomes persist across racial, income, and insurance groups.
Purpose of the Study:
- To examine the associations between race, socioeconomic factors, and AP etiologies and outcomes.
- To evaluate the relationship between comorbidities and adverse AP outcomes.
Main Methods:
- Analysis of the Nationwide Inpatient Sample (2015-2020).
- Stratification of AP etiology (idiopathic, biliary, alcohol-induced, drug-induced).
- Utilized SPSS for demographic analysis and logistic regression; SAS for comorbidity analysis.
Main Results:
- Significant racial and socioeconomic differences in AP etiologies observed: Black and Medicaid patients showed higher rates of alcohol-induced AP; Hispanic individuals had higher rates of biliary AP.
- Variations in AP outcomes including mortality, length of stay, and ICU admission were noted.
- Comorbidities like congestive heart failure and pulmonary circulation disorders correlated with outcome variations.
Conclusions:
- Observed demographic disparities underscore the necessity for early identification of vulnerable populations susceptible to AP complications.
- Further research is required to elucidate underlying factors and develop targeted interventions for AP.
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