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Extracorporeal Life Support (ECLS) for Pulmonary Vein Stenosis Interventions

Stephanie M Tsoi1, Roberta L Keller2, Loren D Sacks3,4

  • 1Division of Critical Care Medicine, Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA. Stephanie.Tsoi@ucsf.edu.

Pediatric Cardiology
|August 20, 2026
PubMed

Insights

Veno-arterial extracorporeal life support (VA-ECLS) stabilized critically ill children during complex pulmonary vein stenosis interventions. This approach may improve outcomes for pediatric patients with severe pulmonary vein stenosis.

Area of Science:

  • Cardiology
  • Pediatric Critical Care

Background:

  • Pediatric pulmonary vein stenosis (PVS) presents significant morbidity and mortality risks.
  • Advanced multivessel PVS poses challenges for interventional procedures.

Purpose of the Study:

  • To evaluate the use of veno-arterial extracorporeal life support (VA-ECLS) in pediatric patients undergoing high-risk pulmonary vein interventions.
  • To assess VA-ECLS's role in stabilizing hemodynamics and respiration during complex catheterizations for PVS.

Main Methods:

  • A case series of pediatric patients with advanced multivessel PVS.
  • Cardiac catheterization procedures incorporating VA-ECLS for hemodynamic and respiratory support.
  • Pulmonary vein angioplasty and/or stent placement performed under VA-ECLS.

Main Results:

  • VA-ECLS provided essential hemodynamic and respiratory stabilization during complex interventions.
  • The adjunctive use of VA-ECLS enabled the completion of high-risk procedures in critically ill pediatric patients.
  • Patients who might not have tolerated catheterization without VA-ECLS could undergo necessary interventions.

Conclusions:

  • VA-ECLS can serve as a valuable adjunctive strategy for high-risk catheter-based interventions in pediatric PVS.
  • Careful risk-benefit assessment and specific patient selection are crucial for utilizing VA-ECLS in this context.
  • This approach holds potential for improving quality of life and extending lifespan in pediatric PVS patients.

Keywords:
Cardiac catheterizationExtracorporeal membrane oxygenationPediatricPulmonary vascular disease

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