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Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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Design, synthesis, biological activity and computational simulation evaluation of pyrimidine-2-aminoacetamide

Yi-Xuan Wang1, Shi-Hao Qin1, Qian Liu2

  • 1College of Pharmaceutical Sciences, Institute of Life Science and Green Development, Key Laboratory of Pharmaceutical Quality Control of Hebei Province, State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding, 071002, China.

Medicinal Chemistry Research : an International Journal for Rapid Communications on Design and Mechanisms of Action of Biologically Active Agents
|August 21, 2026
PubMed

Keywords:
Alzheimer’s diseaseAntioxidant activityCholinesterase inhibitorKinetic studyMolecular docking study

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