Related Experiment Video

Updated: Sep 29, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

Identification of the Novel HLA-DRB1*04:407 Allele by Next-Generation Sequencing

Elham Harfouch1, Bénédicte Paré1, Xavier Chamillard1

  • 1EFS Île-de-France, Laboratoire d'Histocompatibilité et d'Immunologie Leuco-Plaquettaire, Créteil, France.

HLA
|September 28, 2026
PubMed

Abstract:

HLA-DRB1*04:407 differs from DRB1*04:01:01:01 by a single missense nucleotide substitution at position 197 in exon 2.

More Related Videos

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
07:26

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment

Published on: July 18, 2017

Related Experiment Videos

Last Updated: Sep 29, 2026

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
08:07

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation

Published on: September 6, 2017

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
07:26

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment

Published on: July 18, 2017

Related Concept Videos

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.

Articles linked to this work by shared authors, journal, and citation graph.

Characterisation of the Novel HLA-A*03:541 Allele by Next-Generation Sequencing.

HLA·2026

Identification of the Novel HLA-DQB1*02:02:41 Allele by Next-Generation Sequencing.

HLA·2026

Characterisation of the Novel HLA-A*23:163 Allele by Next-Generation Sequencing.

HLA·2026

The Novel HLA-DQB1*06:03:60 Allele Identified by Next-Generation Sequencing and Confirmed by Nanopore Sequencing.

HLA·2026

Identification of the Novel HLA-B*57:212 Allele by Next-Generation Sequencing.

HLA·2026

The HLA-A*24:02:190 Allele Identified by Next-Generation Sequencing and Confirmed by Nanopore Sequencing.

HLA·2026

Genetics of Celiac Disease in Southern Brazil: High-Resolution HLA Haplotypes and Non-HLA Polymorphisms.

HLA·2026

Characterisation of the Novel HLA-DQA1*04:01:11 Allele by Next-Generation Sequencing.

HLA·2026

Identification of the Novel HLA-DQB1*02:279 Allele by Next- and Third-Generation Sequencing.

HLA·2026

The Novel HLA-DRB1*10:50 Allele Identified by Next-Generation Sequencing.

HLA·2026

Characterisation of the Novel HLA-DQB1*03:612 Allele by Sequencing-Based Typing.

HLA·2026

Identification of a New HLA-DRB5 Allele in a Chinese Han Individual, HLA-DRB5*01:01:17.

HLA·2026

Discordantly high apolipoprotein B despite normal LDL cholesterol across AHA PREVENT cardiometabolic risk strata among U.S. adults.

Journal of diabetes and metabolic disorders·2026

Pancreatic arteriovenous malformations as a manifestation of hereditary haemorrhagic telangiectasia (Rendu-Osler-Weber disease): a systematic review.

BMJ open gastroenterology·2026

A Rare Case of Uncorrected Tetralogy of Fallot With Right Hemitruncus in an Adult Survivor Highlighting the Role of Cardiac Computed Tomography.

Cureus·2026

Aortic Thrombus: A Rare Cause of Ischemic Stroke.

Cureus·2026

When A Fall Isn't Just a Fall: Delayed Diagnosis of Acquired Hemophilia A in a Nonagenarian Patient.

The American journal of case reports·2026

Intraosseous Bone Marrow Concentrate and Long-Term Procedure-Free Survival in Bilateral Non-Traumatic Ankle Osteoarthritis: A Contralateral-Controlled Study.

Medicina (Kaunas, Lithuania)·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us