Related Experiment Video
Updated: Oct 17, 2026
A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Published on: May 6, 2018
(Immuno-)Histological Analysis of Ewing Sarcoma
David Marcilla1, Isidro Machado2,3,4, Thomas G P Grünewald5,6,7,8
1Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocio University Hospital/CSIC/University of Sevilla/CIBERONC, Seville, Spain.
Abstract:
The diagnosis of Ewing sarcoma requires integrating information from numerous techniques, some of which are very sophisticated. However, the first steps of the diagnostic process are crucial to achieve the maximum possible diagnostic performance. In this chapter, we will review how to handle the diagnostic specimen from its collection, how to prepare it for diagnosis, how to make a complete pathology report, and provide guidance for the reasonable use of immunohistochemical techniques in this malignancy.
