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Validation and Reliability of the Turkish Version of the Inflammatory Bowel Disease-Disk in Patients with
Tugba Tolu1, Yasemin Kaldirim Armutcuoglu1, Tuba Yilmaz Yildirim1
1Department of Gastroenterology, Marmara University School of Medicine, İstanbul, Türkiye.
Background/Aims:
The inflammatory bowel disease-disk (IBD-Disk) is a visual patient reported outcome measure designed to assess disease-related burden in patients with IBD. This study aimed to translate and culturally adapt the IBD-Disk into Turkish and evaluate its psychometric performance and association with clinical disease activity.
Materials And Methods:
This prospective validation study was conducted between July 2025 and April 2026 at a tertiary referral center. The IBD-Disk was translated using a standardized forward-backward methodology and pilot tested. Assessments were performed at baseline, after 2 weeks in a clinically stable subgroup to evaluate test-retest reliability, and at 6-month follow-up. Disease activity was assessed using the Harvey-Bradshaw Index for Crohn's disease (CD), partial Mayo score for ulcerative colitis (UC), and the Physician Global Assessment (PGA).
Results:
A total of 202 patients were included, comprising 114 with CD and 88 with UC; 136 patients had complete longitudinal data. The Turkish IBD-Disk demonstrated high internal consistency (Cronbach's α = 0.884) and moderate test-retest reliability (intraclass correlation coefficient = 0.68; 95% CI, 0.16-0.90). IBD-Disk scores were moderately correlated with disease activity indices in patients with CD and UC (ρ = 0.525 and ρ = 0.503, respectively; both P < .001) and differed significantly across PGA categories (P < .001). The instrument demonstrated moderate accuracy for detecting active disease (area under the curve = 0.72; 95% CI, 0.65-0.79), with a preliminary receiver operating characteristic-derived cutoff of ≥27.5 (sensitivity 76.1%, specificity 60.5%). Scores decreased significantly among patients with clinical improvement at follow-up (P < .001).
Conclusion:
The Turkish version of the IBD-Disk demonstrated acceptable validity and reliability for assessing patient-perceived disease burden in patients with IBD and demonstrated responsiveness to clinical improvement.
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