[State of the external secretory function of the pancreas in chronic enterocolitis]

Activities of main pancreatic enzymes as well as activity of trypsin inhibitor were studied in blood serum, duodenal contents and urine in course of investigations of the exocrinic function of pancreas in patients. The exocrinic function of pancreas was found to be impaired in chronic enterocolitis. The impairment of the gland secretion, caused by inflammatory and atrophic alterations in intestine, might be one of the factors responsible for alterations in the enzymatic activity and in activity of trypsin inhibitor. Complex examination of the pancreatic enzymes and of trypsin inhibitor supplied an adequate information on the state of exocrinic function of pancreatic gland in the patients with chronic enterocolitis.