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Dysthyroid ophthalmopathy in children
Journal of Pediatric Ophthalmology and Strabismus
|March 1, 1979
Summary
Ocular changes in pediatric thyroid dysfunction are rare and mild. While clinical signs are absent, B Scan Ultrasonography revealed extraocular muscle issues, suggesting conservative management may prevent severe eye complications.
Area of Science:
- Ophthalmology
- Endocrinology
- Pediatrics
Background:
- Thyroid dysfunction can affect various organs, including the eyes.
- Ocular complications in pediatric patients with thyroid disease are not well-documented.
- Previous studies suggest a higher incidence of ophthalmopathy in adults.
Purpose of the Study:
- To investigate the prevalence and severity of ocular changes in pediatric patients with thyroid dysfunction.
- To compare ocular findings with HLA antigen prevalence.
- To explore the role of medical management in preventing ophthalmopathy.
Main Methods:
- Study included 33 pediatric patients diagnosed with thyroid dysfunction.
- Ophthalmological examinations were performed to assess for clinical signs of myopathy, corneal involvement, and visual loss.
- B Scan Ultrasonography was utilized to detect subclinical extraocular muscle abnormalities.
- HLA antigen typing was conducted for patients with and without ophthalmopathy.
Main Results:
- Ocular changes were uncommon and mild in the pediatric cohort.
- No patients presented with clinical myopathy, corneal issues, or vision impairment.
- B Scan Ultrasonography identified extraocular muscle involvement in the absence of clinical symptoms.
- No significant difference in HLA antigen prevalence was observed between patients with and without ophthalmopathy.
Conclusions:
- Ocular complications are infrequent and generally mild in pediatric thyroid dysfunction.
- Subclinical extraocular muscle involvement can be detected via ultrasonography.
- Conservative medical management might contribute to the low incidence of severe ocular manifestations in this age group.