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Bilateral Duane's syndrome associated with crocodile tears
Journal of Pediatric Ophthalmology and Strabismus
|March 1, 1979
Summary
This study presents a rare case of bilateral Duane's retraction syndrome and congenital crocodile tears, suggesting a shared central nervous system origin for these paradoxical innervation syndromes.
Area of Science:
- Neurology
- Ophthalmology
- Genetics
Background:
- Duane's retraction syndrome (DRS) is a congenital eye movement disorder characterized by limited horizontal eye movement and globe retraction.
- Congenital crocodile tears (CCT), or Bogorad's syndrome, involves aberrant lacrimation during mastication.
Observation:
- This report details the rare co-occurrence of bilateral DRS and CCT in a single patient.
- Both conditions represent rare syndromes of paradoxical innervation.
Findings:
- The simultaneous presence of bilateral DRS and CCT suggests a potential shared central nervous system etiology.
- A central localization is hypothesized to explain the simultaneous occurrence of these two distinct neurological anomalies.
Implications:
- Understanding the central mechanisms underlying these rare associations can advance knowledge of cranial nerve development and function.
- This case may inform diagnostic approaches and genetic counseling for patients presenting with either condition individually.