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[Electronmicroscopic studies of the trabecular meshwork in corticosteroid glaucoma]
Klinische Monatsblatter Fur Augenheilkunde
|March 1, 1979
Summary
Cortisone-induced glaucoma in a 41-year-old patient showed massive deposits in the trabecular meshwork, obstructing aqueous humor outflow. These unique deposits distinguish cortisone glaucoma from other forms like glaucoma simplex.
Area of Science:
- Ophthalmology
- Cell Biology
Background:
- Cortisone-induced glaucoma is a significant clinical condition.
- Understanding the underlying pathophysiology is crucial for effective management.
Observation:
- Electron microscopy revealed massive, band-like depositions in the cribriform area and lamellae of the trabeculum corneoscleare.
- These deposits almost completely obstructed aqueous humor pathways.
Findings:
- The observed deposits led to increased outflow resistance, a hallmark of glaucoma.
- Degenerative changes and reduced cell numbers were noted in the affected trabecular cells.
Implications:
- These characteristic deposits differentiate cortisone glaucoma from other glaucoma types, including glaucoma simplex.
- This finding aids in the diagnosis and understanding of steroid-induced ocular hypertension.