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[Seminal infection and male sterility]
Archivos Espanoles De Urologia
|July 1, 1979
Summary
Vesicular prostate pathology in infertile men can be treated effectively with antibiotics like trimethoprim-sulfamethoxazole, improving sperm parameters and leading to pregnancy in some cases.
Area of Science:
- Urology
- Andrology
- Microbiology
Context:
- Vesicular prostate pathology is a significant cause of male infertility.
- Seminal fluid analysis and cultures are crucial for diagnosing prostate infections impacting fertility.
Purpose:
- To investigate the efficacy of antibiotic treatment for infertile patients with vesicular prostate pathology.
- To evaluate the impact of treatment on seminal fluid parameters and pregnancy rates.
Summary:
- A study of 25 infertile men with vesicular prostate pathology assessed various seminal parameters and performed seminal fluid cultures, with 76% showing positive results.
- Treatment with trimethoprim-sulfamethoxazole (TMP-SMZ), often combined with erythromycin, was administered to 22 patients.
- Spermiogram normalization occurred in 38% of treated patients, with one pregnancy; asthenozoospermias showed the best response to TMP-SMZ and erythromycin.
Impact:
- Antibiotic therapy, particularly TMP-SMZ, can improve sperm quality in men with prostate infections and infertility.
- Successful treatment may lead to improved fertility outcomes, including pregnancy.
- Further research is needed to fully elucidate the role of specific antibiotics and treatment protocols.