Chemical structure-activity correlation in the O-methylation of substituted catechols by catechol O-methyltransferase

Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.

Journal of medicinal chemistry·2001

Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor.

Bioorganic & medicinal chemistry letters·2001

Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.

Journal of medicinal chemistry·2001

The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type.

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Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues.

Journal of medicinal chemistry·2001

Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.

Journal of medicinal chemistry·2000

Piezo1 agonists are potent off-target inhibitors of the Kv1.3 channel via gating modification.

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Panoramic characterization of proposed ligands for GPR3: oleoylethanolamide as a pharmacological chaperone.

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Roles of the phosphorylation sites of distinct α1A-adrenergic receptor domains.

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A-kinase anchoring protein complexes and cAMP signaling within the dorsal root ganglia in chronic pain.

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An integrated structural and functional profiling approach uncovers the mechanisms of pregnane X receptor binding and activation by pharmaceutical and environmental compounds.

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Update to RIFM fragrance ingredient safety assessment, methyl cis-5-octenoate, CAS Registry Number 41654-15-3.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2026

Hepatoprotective effects of cinnamic acid against carbon tetrachloride-induced liver injury in a mouse model.

Molecular biology reports·2026

Crystal structure of fucoxanthin: resolving a long-standing crystallographic challenge.

Acta crystallographica. Section C, Structural chemistry·2026

Illuminating Olympicenes: Insights Into Anti-Kasha Photophysics in Polycyclic Aromatic Hydrocarbons.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026

RNAi-Mediated Knockdown of Halloween Genes in Lygus hesperus Has Varied Effects on Oogenesis and Fertility.

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Chemical structure-activity correlation in the O-methylation of substituted catechols by catechol O-methyltransferase

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Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.

Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor.

Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.

The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type.

Synthesis and in vitro and in vivo activity of (-)-(1R,5R,9R)- and (+)-(1S,5S,9S)-N-alkenyl-, -N-alkynyl-, and -N-cyanoalkyl-5, 9-dimethyl-2'-hydroxy-6,7-benzomorphan homologues.

Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.

Piezo1 agonists are potent off-target inhibitors of the Kv1.3 channel via gating modification.

Panoramic characterization of proposed ligands for GPR3: oleoylethanolamide as a pharmacological chaperone.

Roles of the phosphorylation sites of distinct α1A-adrenergic receptor domains.

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Update to RIFM fragrance ingredient safety assessment, methyl cis-5-octenoate, CAS Registry Number 41654-15-3.

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Illuminating Olympicenes: Insights Into Anti-Kasha Photophysics in Polycyclic Aromatic Hydrocarbons.

RNAi-Mediated Knockdown of Halloween Genes in Lygus hesperus Has Varied Effects on Oogenesis and Fertility.

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Chemical structure-activity correlation in the O-methylation of substituted catechols by catechol O-methyltransferase

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