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Hyperprolactinemia and primary amenorrhea.

E Kemmann, J R Jones

    Obstetrics and Gynecology
    |December 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    This study presents four women with primary amenorrhea and hyperprolactinemia, exploring causes and outcomes. Hyperprolactinemia is common in normogonadotropic primary amenorrhea, while primary amenorrhea is rare in hyperprolactinemia.

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    Area of Science:

    • Endocrinology
    • Reproductive Medicine

    Background:

    • Primary amenorrhea, the absence of menses, can stem from various endocrine disruptions.
    • Hyperprolactinemia, elevated prolactin levels, is a known factor affecting reproductive function.

    Purpose of the Study:

    • To present cases of primary amenorrhea associated with hyperprolactinemia.
    • To discuss the underlying causes and clinical follow-up of hyperprolactinemia in these patients.
    • To clarify the prevalence of hyperprolactinemia in primary amenorrhea and vice versa.

    Main Methods:

    • Case series presentation of four women with primary amenorrhea and hyperprolactinemia.
    • Clinical evaluation including assessment for hypothyroidism.
    • Discussion of etiological factors and patient follow-up.

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    Main Results:

    • Four women with normogonadotropic primary amenorrhea and hyperprolactinemia are described.
    • Hypothyroidism was not a contributing factor in these cases.
    • Hyperprolactinemia occurs in approximately one-third of women with normogonadotropic primary amenorrhea.

    Conclusions:

    • Hyperprolactinemia is a significant consideration in the evaluation of normogonadotropic primary amenorrhea.
    • Primary amenorrhea is an infrequent finding in women with hyperprolactinemia.