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Proliferative effect of lithocholic acid on rat liver cell in culture
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.]
|November 1, 1979
Abstract:
In contrast to cholic acid, deoxycholic acid and chenodeoxycholic acid, lithocholic acid (LCA) enhances the growth of rat liver cells in culture. Enhanced proliferation of LCA-treated rat liver cells persists even 12 days after LCA was removed. These findings could suggest a mutagenic effect of LCA, or a metabolite, on rat liver cells.