Comparative endothelial biomicroscopy

Calibrating comparative endothelial biomicroscopy with a corneal endothelial microscope (Heyer-Schulte Medical Optics), we have obtained clinically useful estimates of endothelial cell density. This simple and inexpensive technique allows rapid examination and evaluation of a large number of endothelial cells across various corneal diameters. It is, however, a clinical rather than investigative procedure and is not intended to replace the quantitative features of endothelial specular photomicrography for scientific studies.