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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
[Knowledge of Solomon's epidermal nevus syndrome (author's transl)]
Abstract:
Solomon's epidermal nevus syndrome is a questionable entity, because of its clinical heterogeneity. Four cases are presented in this paper, with emphasis on the complex relationship between variable types of epidermal nevi and diverse kinds of associated nervous, ocular and bone abnormalities. Nevertheless, it is of practical interest to know the frequency and the variability of these ectodermal and mesodermal associated defects; whatever the epidermal nevus, a careful examination must be carried out, in search of ocular, nervous, bone and renal signs, and, less frequently, but more often than in other children, these patients seem to be exposed to visceral malignancies.
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