Experimental production of varicocele and its effect on testes

Parital obstruction of left renal vein leads to production of varicocele in a fairly short period, i.e.; even within a month. Collateral venous channels play an important role in the formation and degree of varicocele. Varicocele has got a depressive effect on the spermatogenesis on the side of varicocele as well as on opposite testes. Leydig cells and interstitial tissue flourish at the expense of gonadal elements. The factors affecting the spermatogenesis are different from those of other tissues of the testes.