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Related Experiment Videos

Lupus mastitis.

R B Harris, R K Winkelmann

    Archives of Dermatology
    |March 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Lupus mastitis, a rare breast inflammation linked to lupus erythematosus, can mimic breast cancer on mammograms. Prompt diagnosis and antimalarial treatment led to full recovery in two patients.

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    Area of Science:

    • Dermatology
    • Rheumatology
    • Oncology

    Background:

    • Discoid lupus erythematosus (DLE) is a chronic autoimmune condition.
    • Breast involvement in DLE is rare, presenting diagnostic challenges.
    • Mammographic findings can be mistaken for malignancy.

    Observation:

    • Two patients with DLE presented with painful breast nodules.
    • Mammograms suggested breast carcinoma in both cases.
    • Histopathology and immunofluorescence confirmed lupus mastitis.

    Findings:

    • Lupus mastitis was diagnosed based on clinical, histological, and immunofluorescence data.
    • The condition mimicked breast cancer on imaging.
    • Antimalarial therapy was effective.

    Implications:

    • Lupus mastitis should be considered in patients with DLE and breast lesions.
    • Early diagnosis prevents unnecessary surgical intervention.
    • Effective treatment with antimalarials offers a favorable prognosis.